Compromised Biomechanical Properties, Cell–Cell Adhesion and Nanotubes Communication in Cardiac Fibroblasts Carrying the Lamin A/C D192G Mutation

Clinical effects induced by arrhythmogenic cardiomyopathy (ACM) originate from a large spectrum of genetic variations, including the missense mutation of the lamin A/C gene (LMNA), LMNA D192G. The aim of our study was to investigate the biophysical and biomechanical impact of the LMNA D192G mutation...

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Detalles Bibliográficos
Autores principales: Lachaize, Veronique, Peña, Brisa, Ciubotaru, Catalin, Cojoc, Dan, Chen, Suet Nee, Taylor, Matthew R. G., Mestroni, Luisa, Sbaizero, Orfeo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431729/
https://www.ncbi.nlm.nih.gov/pubmed/34502098
http://dx.doi.org/10.3390/ijms22179193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431729/
https://www.ncbi.nlm.nih.gov/pubmed/34502098
http://dx.doi.org/10.3390/ijms22179193

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