An Overview of the Nrf2/ARE Pathway and Its Role in Neurodegenerative Diseases

Nrf2 is a basic region leucine-zipper transcription factor that plays a pivotal role in the coordinated gene expression of antioxidant and detoxifying enzymes, promoting cell survival in adverse environmental or defective metabolic conditions. After synthesis, Nrf2 is arrested in the cytoplasm by th...

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Detalles Bibliográficos
Autores principales: Zgorzynska, Emilia, Dziedzic, Barbara, Walczewska, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431732/
https://www.ncbi.nlm.nih.gov/pubmed/34502501
http://dx.doi.org/10.3390/ijms22179592

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431732/
https://www.ncbi.nlm.nih.gov/pubmed/34502501
http://dx.doi.org/10.3390/ijms22179592

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