Mice with Whole-Body Disruption of AMPK-Glycogen Binding Have Increased Adiposity, Reduced Fat Oxidation and Altered Tissue Glycogen Dynamics

The AMP-activated protein kinase (AMPK), a central regulator of cellular energy balance and metabolism, binds glycogen via its β subunit. However, the physiological effects of disrupting AMPK-glycogen interactions remain incompletely understood. To chronically disrupt AMPK-glycogen binding, AMPK β d...

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Detalles Bibliográficos
Autores principales: Janzen, Natalie R., Whitfield, Jamie, Murray-Segal, Lisa, Kemp, Bruce E., Hawley, John A., Hoffman, Nolan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431764/
https://www.ncbi.nlm.nih.gov/pubmed/34502525
http://dx.doi.org/10.3390/ijms22179616

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431764/
https://www.ncbi.nlm.nih.gov/pubmed/34502525
http://dx.doi.org/10.3390/ijms22179616

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