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Impact of Amyloid-β on Platelet Mitochondrial Function and Platelet–Mediated Amyloid Aggregation in Alzheimer’s Disease

Background: Alzheimer’s disease (AD) is characterized by an accumulation of amyloid β (Aβ) peptides in the brain and mitochondrial dysfunction. Platelet activation is enhanced in AD and platelets contribute to AD pathology by their ability to facilitate soluble Aβ to form Aβ aggregates. Thus, anti-p...

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Detalles Bibliográficos
Autores principales: Donner, Lili, Feige, Tobias, Freiburg, Carolin, Toska, Laura Mara, Reichert, Andreas S., Chatterjee, Madhumita, Elvers, Margitta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431787/
https://www.ncbi.nlm.nih.gov/pubmed/34502546
http://dx.doi.org/10.3390/ijms22179633