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Exosomes Secreted by Adipose-Derived Stem Cells Following FK506 Stimulation Reduce Autophagy of Macrophages in Spine after Nerve Crush Injury

Macrophages emerge in the milieu around innervated neurons after nerve injuries. Following nerve injury, autophagy is induced in macrophages and affects the regulation of inflammatory responses. It is closely linked to neuroinflammation, while the immunosuppressive drug tacrolimus (FK506) enhances n...

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Detalles Bibliográficos
Autores principales: Kuo, Pao-Jen, Rau, Cheng-Shyuan, Wu, Shao-Chun, Lin, Chia-Wei, Huang, Lien-Hung, Lu, Tsu-Hsiang, Wu, Yi-Chan, Wu, Chia-Jung, Tsai, Chia-Wen, Hsieh, Ching-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431814/
https://www.ncbi.nlm.nih.gov/pubmed/34502537
http://dx.doi.org/10.3390/ijms22179628