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Exosomes Secreted by Adipose-Derived Stem Cells Following FK506 Stimulation Reduce Autophagy of Macrophages in Spine after Nerve Crush Injury
Macrophages emerge in the milieu around innervated neurons after nerve injuries. Following nerve injury, autophagy is induced in macrophages and affects the regulation of inflammatory responses. It is closely linked to neuroinflammation, while the immunosuppressive drug tacrolimus (FK506) enhances n...
Autores principales: | Kuo, Pao-Jen, Rau, Cheng-Shyuan, Wu, Shao-Chun, Lin, Chia-Wei, Huang, Lien-Hung, Lu, Tsu-Hsiang, Wu, Yi-Chan, Wu, Chia-Jung, Tsai, Chia-Wen, Hsieh, Ching-Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431814/ https://www.ncbi.nlm.nih.gov/pubmed/34502537 http://dx.doi.org/10.3390/ijms22179628 |
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