Human amniotic stem cells-derived exosmal miR-181a-5p and miR-199a inhibit melanogenesis and promote melanosome degradation in skin hyperpigmentation, respectively

BACKGROUND: Hyperpigmentation of skin is caused by an imbalance between the melanosome/melanin synthesis in melanocytes and the melanosome/melanin degradation in keratinocytes. Although studies showed that stem cells play a role in hypopigmentation, the underlying mechanisms are far not elucidated....

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Detalles Bibliográficos
Autores principales: Wang, Xiao-Yu, Guan, Xiao-Hui, Yu, Zhen-Ping, Wu, Jie, Huang, Qi-Ming, Deng, Ke-Yu, Xin, Hong-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431893/
https://www.ncbi.nlm.nih.gov/pubmed/34507619
http://dx.doi.org/10.1186/s13287-021-02570-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431893/
https://www.ncbi.nlm.nih.gov/pubmed/34507619
http://dx.doi.org/10.1186/s13287-021-02570-9

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