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Human amniotic stem cells-derived exosmal miR-181a-5p and miR-199a inhibit melanogenesis and promote melanosome degradation in skin hyperpigmentation, respectively

BACKGROUND: Hyperpigmentation of skin is caused by an imbalance between the melanosome/melanin synthesis in melanocytes and the melanosome/melanin degradation in keratinocytes. Although studies showed that stem cells play a role in hypopigmentation, the underlying mechanisms are far not elucidated....

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Detalles Bibliográficos
Autores principales:	Wang, Xiao-Yu, Guan, Xiao-Hui, Yu, Zhen-Ping, Wu, Jie, Huang, Qi-Ming, Deng, Ke-Yu, Xin, Hong-Bo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431893/ https://www.ncbi.nlm.nih.gov/pubmed/34507619 http://dx.doi.org/10.1186/s13287-021-02570-9

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