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Exogenous Aβ seeds induce Aβ depositions in the blood vessels rather than the brain parenchyma, independently of Aβ strain-specific information

Little is known about the effects of parenchymal or vascular amyloid β peptide (Aβ) deposition in the brain. We hypothesized that Aβ strain-specific information defines whether Aβ deposits on the brain parenchyma or blood vessels. We investigated 12 autopsied patients with different severities of Aβ...

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Detalles Bibliográficos
Autores principales: Hamaguchi, Tsuyoshi, Kim, Jee Hee, Hasegawa, Akane, Goto, Ritsuko, Sakai, Kenji, Ono, Kenjiro, Itoh, Yoshinori, Yamada, Masahito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431898/
https://www.ncbi.nlm.nih.gov/pubmed/34507620
http://dx.doi.org/10.1186/s40478-021-01252-0