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Exogenous Aβ seeds induce Aβ depositions in the blood vessels rather than the brain parenchyma, independently of Aβ strain-specific information
Little is known about the effects of parenchymal or vascular amyloid β peptide (Aβ) deposition in the brain. We hypothesized that Aβ strain-specific information defines whether Aβ deposits on the brain parenchyma or blood vessels. We investigated 12 autopsied patients with different severities of Aβ...
Autores principales: | Hamaguchi, Tsuyoshi, Kim, Jee Hee, Hasegawa, Akane, Goto, Ritsuko, Sakai, Kenji, Ono, Kenjiro, Itoh, Yoshinori, Yamada, Masahito |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431898/ https://www.ncbi.nlm.nih.gov/pubmed/34507620 http://dx.doi.org/10.1186/s40478-021-01252-0 |
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