Non-cancer-related pathogenic germline variants and expression consequences in ten-thousand cancer genomes

BACKGROUND: DNA sequencing is increasingly incorporated into the routine care of cancer patients, many of whom also carry inherited, moderate/high-penetrance variants associated with other diseases. Yet, the prevalence and consequence of such variants remain unclear. METHODS: We analyzed the germlin...

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Detalles Bibliográficos
Autores principales: Wang, Zishan, Fan, Xiao, Shen, Yufeng, Pagadala, Meghana S, Signer, Rebecca, Cygan, Kamil J., Fairbrother, William G., Carter, Hannah, Chung, Wendy K., Huang, Kuan-lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431938/
https://www.ncbi.nlm.nih.gov/pubmed/34503567
http://dx.doi.org/10.1186/s13073-021-00964-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431938/
https://www.ncbi.nlm.nih.gov/pubmed/34503567
http://dx.doi.org/10.1186/s13073-021-00964-1

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