Genotype, Age, Genetic Background, and Sex Influence Epha2-Related Cataract Development in Mice

PURPOSE: Age-related cataract is the leading cause of blindness worldwide. Variants in the EPHA2 gene increase the disease risk, and its knockout in mice causes cataract. We investigated whether age, sex, and genetic background, risk factors for age-related cataract, and Epha2 genotype influence Eph...

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Detalles Bibliográficos
Autores principales: Dave, Alpana, Craig, Jamie E., Alamein, Mohammad, Skrzypiec, Karina, Beltz, Justin, Pfaff, Annalise, Burdon, Kathryn P., Ercal, Nuran, de Iongh, Robb U., Sharma, Shiwani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431977/
https://www.ncbi.nlm.nih.gov/pubmed/34495288
http://dx.doi.org/10.1167/iovs.62.12.3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8431977/
https://www.ncbi.nlm.nih.gov/pubmed/34495288
http://dx.doi.org/10.1167/iovs.62.12.3

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