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+3179G/A Insulin-Like Growth Factor-1 Receptor Polymorphism: A Novel Susceptibility Contributor in Anti-Ro/SSA Positive Patients with Sjögren’s Syndrome: Potential Clinical and Pathogenetic Implications

Background: Alterations of the insulin-like growth factor (IGF) pathway along with genetic variations of the IGF1 receptor (IGF1R) gene have been linked to the development of systemic autoimmunity, possibly through apoptosis induction. This study aims to investigate whether genetic variations of the...

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Detalles Bibliográficos
Autores principales: Skarlis, Charalampos, Marketos, Nikolaos, Nezos, Adrianos, Papanikolaou, Asimina, Voulgarelis, Michael, Koutsilieris, Michael, Moutsopoulos, Haralampos M., Mavragani, Clio P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8432056/
https://www.ncbi.nlm.nih.gov/pubmed/34501407
http://dx.doi.org/10.3390/jcm10173960