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Properties of Transport Mediated by the Human Organic Cation Transporter 2 Studied in a Polarized Three-Dimensional Epithelial Cell Culture Model

The renal secretory clearance for organic cations (neurotransmitters, metabolism products and drugs) is mediated by transporters specifically expressed in the basolateral and apical plasma membrane domains of proximal tubule cells. Here, human organic cation transporter 2 (hOCT2) is the main transpo...

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Detalles Bibliográficos
Autores principales: Koepp, Tim N., Tokaj, Alexander, Nedvetsky, Pavel I., Conchon Costa, Ana Carolina, Snieder, Beatrice, Schröter, Rita, Ciarimboli, Giuliano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8432172/
https://www.ncbi.nlm.nih.gov/pubmed/34502566
http://dx.doi.org/10.3390/ijms22179658