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Differential Impact of Cytochrome 2C19 Allelic Variants on Three Different Platelet Function Tests in Clopidogrel-Treated Patients

On-treatment platelet reactivity in clopidogrel-treated patients can be measured with several platelet function tests (PFTs). However, the agreement between different PFTs is only slight to moderate. Polymorphisms of the CYP2C19 gene have an impact on the metabolization of clopidogrel and, thereby,...

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Detalles Bibliográficos
Autores principales: Olie, Renske H., Hensgens, Rachelle R. K., Wijnen, Petal A. H. M., Veenstra, Leo F., de Greef, Bianca T. A., Vries, Minka J. A., van der Meijden, Paola E. J., ten Berg, Jurriën M., ten Cate, Hugo, Bekers, Otto, Henskens, Yvonne M. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8432532/
https://www.ncbi.nlm.nih.gov/pubmed/34501440
http://dx.doi.org/10.3390/jcm10173992