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Genetics Variants in the Epoxygenase Pathway of Arachidonic Metabolism Are Associated with Eicosanoids Levels and the Risk of Diabetic Nephropathy

Genes in the epoxygenase pathway of arachidonic acid metabolism leading to vasoactive eicosanoids, mainly 20-hydroxyeicosatetraenoic (20-HETE) and epoxyeicosatrienoic (EETs) acids, have been related to glucose-induced renal damage in preclinical reports. We genotyped 1088 diabetic kidney disease (DK...

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Detalles Bibliográficos
Autores principales: Mota-Zamorano, Sonia, Robles, Nicolás R., González, Luz M., Valdivielso, José M., Lopez-Gomez, Juan, Cancho, Bárbara, García-Pino, Guadalupe, Gervasini, Guillermo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8432556/
https://www.ncbi.nlm.nih.gov/pubmed/34501433
http://dx.doi.org/10.3390/jcm10173980