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Nasal alum-adjuvanted vaccine promotes IL-33 release from alveolar epithelial cells that elicits IgA production via type 2 immune responses

Aluminum hydroxide salts (alum) have been added to inactivated vaccines as safe and effective adjuvants to increase the effectiveness of vaccination. However, the exact cell types and immunological factors that initiate mucosal immune responses to alum adjuvants are unclear. In this study, the mecha...

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Detalles Bibliográficos
Autores principales: Sasaki, Eita, Asanuma, Hideki, Momose, Haruka, Furuhata, Keiko, Mizukami, Takuo, Hamaguchi, Isao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8432758/
https://www.ncbi.nlm.nih.gov/pubmed/34460865
http://dx.doi.org/10.1371/journal.ppat.1009890