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Comparative analysis of the ex vivo IFN-gamma responses to CD8+ T cell epitopes within allelic forms of PfAMA1 in subjects with natural exposure to malaria

Antigen polymorphisms in essential malarial antigens are a key challenge to the design and development of broadly effective malaria vaccines. The effect of polymorphisms on antibody responses is fairly well studied while much fewer studies have assessed this for T cell responses. This study investig...

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Detalles Bibliográficos
Autores principales: Nlinwe, Omarine N., Ofori, Ebenezer A., Akyea-Mensah, Kwadwo, Kyei-Baafour, Eric, Ganeshan, Harini, Belmonte, Maria, Peters, Bjoern, Villasante, Eileen, Sedegah, Martha, Kusi, Kwadwo Asamoah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8432784/
https://www.ncbi.nlm.nih.gov/pubmed/34506564
http://dx.doi.org/10.1371/journal.pone.0257219