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Medial prefrontal area reductions, altered expressions of cholecystokinin, parvalbumin, and activating transcription factor 4 in the corticolimbic system, and altered emotional behavior in a progressive rat model of type 2 diabetes

Metabolic disorders are associated with a higher risk of psychiatric disorders. We previously reported that 20-week-old Otsuka Long-Evans Tokushima fatty (OLETF) rats, a model of progressive type 2 diabetes, showed increased anxiety-like behavior and regional area reductions and increased cholecysto...

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Detalles Bibliográficos
Autores principales: Ochi, Ryosuke, Fujita, Naoto, Goto, Natsuki, Takaishi, Kaho, Oshima, Takaya, Nguyen, Son Tien, Nishijo, Hisao, Urakawa, Susumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8432800/
https://www.ncbi.nlm.nih.gov/pubmed/34506507
http://dx.doi.org/10.1371/journal.pone.0256655