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Medial prefrontal area reductions, altered expressions of cholecystokinin, parvalbumin, and activating transcription factor 4 in the corticolimbic system, and altered emotional behavior in a progressive rat model of type 2 diabetes
Metabolic disorders are associated with a higher risk of psychiatric disorders. We previously reported that 20-week-old Otsuka Long-Evans Tokushima fatty (OLETF) rats, a model of progressive type 2 diabetes, showed increased anxiety-like behavior and regional area reductions and increased cholecysto...
Autores principales: | Ochi, Ryosuke, Fujita, Naoto, Goto, Natsuki, Takaishi, Kaho, Oshima, Takaya, Nguyen, Son Tien, Nishijo, Hisao, Urakawa, Susumu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8432800/ https://www.ncbi.nlm.nih.gov/pubmed/34506507 http://dx.doi.org/10.1371/journal.pone.0256655 |
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