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Predicting drug sensitivity of cancer cells based on DNA methylation levels

Cancer cell lines, which are cell cultures derived from tumor samples, represent one of the least expensive and most studied preclinical models for drug development. Accurately predicting drug responses for a given cell line based on molecular features may help to optimize drug-development pipelines...

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Detalles Bibliográficos
Autores principales: Miranda, Sofia P., Baião, Fernanda A., Fleck, Julia L., Piccolo, Stephen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8432830/
https://www.ncbi.nlm.nih.gov/pubmed/34506489
http://dx.doi.org/10.1371/journal.pone.0238757