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Predicting drug sensitivity of cancer cells based on DNA methylation levels
Cancer cell lines, which are cell cultures derived from tumor samples, represent one of the least expensive and most studied preclinical models for drug development. Accurately predicting drug responses for a given cell line based on molecular features may help to optimize drug-development pipelines...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8432830/ https://www.ncbi.nlm.nih.gov/pubmed/34506489 http://dx.doi.org/10.1371/journal.pone.0238757 |