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Mediator complex proximal Tail subunit MED30 is critical for Mediator core stability and cardiomyocyte transcriptional network

Dysregulation of cardiac transcription programs has been identified in patients and families with heart failure, as well as those with morphological and functional forms of congenital heart defects. Mediator is a multi-subunit complex that plays a central role in transcription initiation by integrat...

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Detalles Bibliográficos
Autores principales: Tan, Changming, Zhu, Siting, Chen, Zee, Liu, Canzhao, Li, Yang E., Zhu, Mason, Zhang, Zhiyuan, Zhang, Zhiwei, Zhang, Lunfeng, Gu, Yusu, Liang, Zhengyu, Boyer, Thomas G., Ouyang, Kunfu, Evans, Sylvia M., Fang, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8432849/
https://www.ncbi.nlm.nih.gov/pubmed/34506481
http://dx.doi.org/10.1371/journal.pgen.1009785