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Mediator complex proximal Tail subunit MED30 is critical for Mediator core stability and cardiomyocyte transcriptional network
Dysregulation of cardiac transcription programs has been identified in patients and families with heart failure, as well as those with morphological and functional forms of congenital heart defects. Mediator is a multi-subunit complex that plays a central role in transcription initiation by integrat...
Autores principales: | Tan, Changming, Zhu, Siting, Chen, Zee, Liu, Canzhao, Li, Yang E., Zhu, Mason, Zhang, Zhiyuan, Zhang, Zhiwei, Zhang, Lunfeng, Gu, Yusu, Liang, Zhengyu, Boyer, Thomas G., Ouyang, Kunfu, Evans, Sylvia M., Fang, Xi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8432849/ https://www.ncbi.nlm.nih.gov/pubmed/34506481 http://dx.doi.org/10.1371/journal.pgen.1009785 |
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