Myeloid neddylation targets IRF7 and promotes host innate immunity against RNA viruses

Neddylation, an important type of post-translational modification, has been implicated in innate and adapted immunity. But the role of neddylation in innate immune response against RNA viruses remains elusive. Here we report that neddylation promotes RNA virus-induced type I IFN production, especial...

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Detalles Bibliográficos
Autores principales: Zhao, Min, Zhang, Yaolin, Yang, Xiqin, Jin, Jiayang, Shen, Zhuo, Feng, Xiaoyao, Zou, Tao, Deng, Lijiao, Cheng, Daohai, Zhang, Xueting, Qin, Cheng, Niu, Chunxiao, Ye, Zhenjie, Zhang, Xueying, He, Jia, Hou, Chunmei, Li, Ge, Han, Gencheng, Cheng, Qianqian, Wang, Qingyang, Wei, Lin, Dong, Jie, Zhang, Jiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8432861/
https://www.ncbi.nlm.nih.gov/pubmed/34506605
http://dx.doi.org/10.1371/journal.ppat.1009901

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8432861/
https://www.ncbi.nlm.nih.gov/pubmed/34506605
http://dx.doi.org/10.1371/journal.ppat.1009901

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