Dabrafenib, idelalisib and nintedanib act as significant allosteric modulator for dengue NS3 protease

Dengue virus (DENV) encodes a unique protease (NS3/NS2B) essential for its maturation and infectivity and, it has become a key target for anti-viral drug design to treat dengue and other flavivirus related infections. Present investigation established that some of the drug molecules currently used m...

Descripción completa

Detalles Bibliográficos
Autores principales: Uday, R. V. Sriram, Misra, Rajdip, Harika, Annaram, Dolui, Sandip, Saha, Achintya, Pal, Uttam, Ravichandiran, V., Maiti, Nakul C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8432871/
https://www.ncbi.nlm.nih.gov/pubmed/34506566
http://dx.doi.org/10.1371/journal.pone.0257206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8432871/
https://www.ncbi.nlm.nih.gov/pubmed/34506566
http://dx.doi.org/10.1371/journal.pone.0257206

Ejemplares similares