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Dabrafenib, idelalisib and nintedanib act as significant allosteric modulator for dengue NS3 protease

Dengue virus (DENV) encodes a unique protease (NS3/NS2B) essential for its maturation and infectivity and, it has become a key target for anti-viral drug design to treat dengue and other flavivirus related infections. Present investigation established that some of the drug molecules currently used m...

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Detalles Bibliográficos
Autores principales:	Uday, R. V. Sriram, Misra, Rajdip, Harika, Annaram, Dolui, Sandip, Saha, Achintya, Pal, Uttam, Ravichandiran, V., Maiti, Nakul C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8432871/ https://www.ncbi.nlm.nih.gov/pubmed/34506566 http://dx.doi.org/10.1371/journal.pone.0257206

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