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A kinase-independent function of PAK is crucial for pathogen-mediated actin remodelling

The p21-activated kinase (PAK) family regulate a multitude of cellular processes, including actin cytoskeleton remodelling. Numerous bacterial pathogens usurp host signalling pathways that regulate actin reorganisation in order to promote Infection. Salmonella and pathogenic Escherichia coli drive a...

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Detalles Bibliográficos
Autores principales: Davidson, Anthony, Tyler, Joe, Hume, Peter, Singh, Vikash, Koronakis, Vassilis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8432889/
https://www.ncbi.nlm.nih.gov/pubmed/34460869
http://dx.doi.org/10.1371/journal.ppat.1009902