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Distinct Metalloproteinase Expression and Functions in Systemic Sclerosis and Fibrosis: What We Know and the Potential for Intervention

Systemic sclerosis (SSc) is a chronic debilitating idiopathic disorder, characterized by deposition of excessive extracellular matrix (ECM) proteins such as collagen which leads to fibrosis of the skin and other internal organs. During normal tissue repair and remodeling, the accumulation and turnov...

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Detalles Bibliográficos
Autores principales: Leong, Edwin, Bezuhly, Michael, Marshall, Jean S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8432940/
https://www.ncbi.nlm.nih.gov/pubmed/34512395
http://dx.doi.org/10.3389/fphys.2021.727451