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MKP-1 Overexpression Reduces Postischemic Myocardial Damage through Attenuation of ER Stress and Mitochondrial Damage

Mitochondrial dysfunction and endoplasmic reticulum (ER) stress contribute to postischemic myocardial damage, but the upstream regulatory mechanisms have not been identified. In this study, we analyzed the role of mitogen-activated protein kinase (MAPK) phosphatase 1 (MKP-1) in the regulation of mit...

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Detalles Bibliográficos
Autores principales: Hou, Xiaoling, Li, Lijun, Chen, Si, Ge, Cheng, Shen, Mingzhi, Fu, Zhenhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433005/
https://www.ncbi.nlm.nih.gov/pubmed/34512872
http://dx.doi.org/10.1155/2021/8905578