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CXCR5 guides migration and tumor eradication of anti-EGFR chimeric antigen receptor T cells

The efficacy of chimeric antigen receptor (CAR) T is still not optimal for solid tumors, partly due to the lack of T cell infiltration to the tumor site. One promising strategy is to guide T cells through tumor-specific chemokines, provided that the matching chemokine receptors are expressed on T ce...

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Detalles Bibliográficos
Autores principales: Li, Guangchao, Guo, Jintao, Zheng, Yanfang, Ding, Wen, Han, Zheping, Qin, Lingyu, Mo, Wenjun, Luo, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433065/
https://www.ncbi.nlm.nih.gov/pubmed/34553036
http://dx.doi.org/10.1016/j.omto.2021.07.003