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CXCR5 guides migration and tumor eradication of anti-EGFR chimeric antigen receptor T cells
The efficacy of chimeric antigen receptor (CAR) T is still not optimal for solid tumors, partly due to the lack of T cell infiltration to the tumor site. One promising strategy is to guide T cells through tumor-specific chemokines, provided that the matching chemokine receptors are expressed on T ce...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society of Gene & Cell Therapy
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433065/ https://www.ncbi.nlm.nih.gov/pubmed/34553036 http://dx.doi.org/10.1016/j.omto.2021.07.003 |