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A novel protein-drug conjugate, SSH20, demonstrates significant efficacy in caveolin-1-expressing tumors

In recent years, human serum albumin (HSA) has been characterized as an ideal drug carrier in the cancer arena. Caveolin-1 (Cav-1) has been established as the principal structural protein of caveolae and, thus, critical for caveolae-mediated endocytosis. Cav-1 has been shown to be overexpressed in c...

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Detalles Bibliográficos
Autores principales: Robb, Ryan, Kuo, Jimmy Chun-Tien, Liu, Yang, Corrales-Guerrero, Sergio, Cui, Tiantian, Hegazi, Ahmad, Nagy, Gregory, Lee, Robert J., Williams, Terence M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433067/
https://www.ncbi.nlm.nih.gov/pubmed/34553040
http://dx.doi.org/10.1016/j.omto.2021.07.013