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A novel protein-drug conjugate, SSH20, demonstrates significant efficacy in caveolin-1-expressing tumors
In recent years, human serum albumin (HSA) has been characterized as an ideal drug carrier in the cancer arena. Caveolin-1 (Cav-1) has been established as the principal structural protein of caveolae and, thus, critical for caveolae-mediated endocytosis. Cav-1 has been shown to be overexpressed in c...
Autores principales: | Robb, Ryan, Kuo, Jimmy Chun-Tien, Liu, Yang, Corrales-Guerrero, Sergio, Cui, Tiantian, Hegazi, Ahmad, Nagy, Gregory, Lee, Robert J., Williams, Terence M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433067/ https://www.ncbi.nlm.nih.gov/pubmed/34553040 http://dx.doi.org/10.1016/j.omto.2021.07.013 |
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