Tripartite motif-containing 3 (TRIM3) enhances ER signaling and confers tamoxifen resistance in breast cancer

Tamoxifen resistance remains a clinical problem in estrogen receptor (ER)-positive breast cancer. SUMOylation of ERα enhances ERα-induced transcription activity. Tripartite motif-containing (TRIM) proteins are a new class of SUMO E3 ligases, which regulate the SUMOylation of proteins. However, the p...

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Detalles Bibliográficos
Autores principales: Ye, Runyi, AiErken, NiJiati, Kuang, Xiaying, Zeng, Huijuan, Shao, Nan, Lin, Ying, Liu, Pian, Wang, Shenming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433133/
https://www.ncbi.nlm.nih.gov/pubmed/34508066
http://dx.doi.org/10.1038/s41389-021-00350-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433133/
https://www.ncbi.nlm.nih.gov/pubmed/34508066
http://dx.doi.org/10.1038/s41389-021-00350-x

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