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Neurodevelopmental impairment induced by prenatal valproic acid exposure shown with the human cortical organoid-on-a-chip model

Prenatal exposure to environmental insults can increase the risk of developing neurodevelopmental disorders. Administration of the antiepileptic drug valproic acid (VPA) during pregnancy is tightly associated with a high risk of neurological disorders in offspring. However, the lack of an ideal huma...

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Detalles Bibliográficos
Autores principales: Cui, Kangli, Wang, Yaqing, Zhu, Yujuan, Tao, Tingting, Yin, Fangchao, Guo, Yaqiong, Liu, Haitao, Li, Fei, Wang, Peng, Chen, Yuejun, Qin, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433196/
https://www.ncbi.nlm.nih.gov/pubmed/34567661
http://dx.doi.org/10.1038/s41378-020-0165-z