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Neurodevelopmental impairment induced by prenatal valproic acid exposure shown with the human cortical organoid-on-a-chip model
Prenatal exposure to environmental insults can increase the risk of developing neurodevelopmental disorders. Administration of the antiepileptic drug valproic acid (VPA) during pregnancy is tightly associated with a high risk of neurological disorders in offspring. However, the lack of an ideal huma...
Autores principales: | Cui, Kangli, Wang, Yaqing, Zhu, Yujuan, Tao, Tingting, Yin, Fangchao, Guo, Yaqiong, Liu, Haitao, Li, Fei, Wang, Peng, Chen, Yuejun, Qin, Jianhua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433196/ https://www.ncbi.nlm.nih.gov/pubmed/34567661 http://dx.doi.org/10.1038/s41378-020-0165-z |
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