In situ cryo-electron tomography reveals gradient organization of ribosome biogenesis in intact nucleoli

Ribosomes comprise a large (LSU) and a small subunit (SSU) which are synthesized independently in the nucleolus before being exported into the cytoplasm, where they assemble into functional ribosomes. Individual maturation steps have been analyzed in detail using biochemical methods, light microscop...

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Detalles Bibliográficos
Autores principales: Erdmann, Philipp S., Hou, Zhen, Klumpe, Sven, Khavnekar, Sagar, Beck, Florian, Wilfling, Florian, Plitzko, Jürgen M., Baumeister, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433212/
https://www.ncbi.nlm.nih.gov/pubmed/34508074
http://dx.doi.org/10.1038/s41467-021-25413-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433212/
https://www.ncbi.nlm.nih.gov/pubmed/34508074
http://dx.doi.org/10.1038/s41467-021-25413-w

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