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In situ cryo-electron tomography reveals gradient organization of ribosome biogenesis in intact nucleoli
Ribosomes comprise a large (LSU) and a small subunit (SSU) which are synthesized independently in the nucleolus before being exported into the cytoplasm, where they assemble into functional ribosomes. Individual maturation steps have been analyzed in detail using biochemical methods, light microscop...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433212/ https://www.ncbi.nlm.nih.gov/pubmed/34508074 http://dx.doi.org/10.1038/s41467-021-25413-w |