Phosphopantetheinyl transferase binding and inhibition by amidino-urea and hydroxypyrimidinethione compounds

Owing to their role in activating enzymes essential for bacterial viability and pathogenicity, phosphopantetheinyl transferases represent novel and attractive drug targets. In this work, we examined the inhibitory effect of the aminido-urea 8918 compound against the phosphopantetheinyl transferases...

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Detalles Bibliográficos
Autores principales: Carivenc, Coralie, Maveyraud, Laurent, Blanger, Claire, Ballereau, Stéphanie, Roy-Camille, Coralie, Nguyen, Minh Chau, Génisson, Yves, Guilhot, Christophe, Chalut, Christian, Pedelacq, Jean-Denis, Mourey, Lionel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433221/
https://www.ncbi.nlm.nih.gov/pubmed/34508141
http://dx.doi.org/10.1038/s41598-021-97197-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433221/
https://www.ncbi.nlm.nih.gov/pubmed/34508141
http://dx.doi.org/10.1038/s41598-021-97197-4

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