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A time-resolved fluorescence resonance energy transfer screening assay for discovery of protein-protein interaction modulators
Protein-protein interactions (PPIs) have emerged as promising yet challenging therapeutic targets. A robust bioassay is required for rapid PPI modulator discovery. Here, we present a time-resolved Förster's (fluorescence) resonance energy transfer assay protocol for PPI modulator screening in a...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433285/ https://www.ncbi.nlm.nih.gov/pubmed/34527960 http://dx.doi.org/10.1016/j.xpro.2021.100804 |