Single-cell lactate production rate as a measure of glycolysis in endothelial cells

Heterogeneous metabolism supports critical single-cell functions. Here, we describe deep-learning-enabled image analyses of a genetically encoded lactate-sensing probe which can accurately quantify metabolite levels and glycolytic rates at the single-cell level. Multiple strategies and test data hav...

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Detalles Bibliográficos
Autores principales: Harrison, Devin, Wu, David, Huang, Jun, Fang, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433287/
https://www.ncbi.nlm.nih.gov/pubmed/34527962
http://dx.doi.org/10.1016/j.xpro.2021.100807

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433287/
https://www.ncbi.nlm.nih.gov/pubmed/34527962
http://dx.doi.org/10.1016/j.xpro.2021.100807

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