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Unified AI framework to uncover deep interrelationships between gene expression and Alzheimer’s disease neuropathologies

Deep neural networks (DNNs) capture complex relationships among variables, however, because they require copious samples, their potential has yet to be fully tapped for understanding relationships between gene expression and human phenotypes. Here we introduce an analysis framework, namely MD-AD (Mu...

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Detalles Bibliográficos
Autores principales: Beebe-Wang, Nicasia, Celik, Safiye, Weinberger, Ethan, Sturmfels, Pascal, De Jager, Philip L., Mostafavi, Sara, Lee, Su-In
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433314/
https://www.ncbi.nlm.nih.gov/pubmed/34508095
http://dx.doi.org/10.1038/s41467-021-25680-7