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Macrophage-derived interleukin-6 is necessary and sufficient for choroidal angiogenesis

Neovascular age-related macular degeneration (nAMD) commonly causes vision loss from aberrant angiogenesis, termed choroidal neovascularization (CNV). Interleukin-6 (IL6) is a pro-inflammatory and pro-angiogenic cytokine that is correlated with AMD progression and nAMD activity. We hypothesize that...

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Detalles Bibliográficos
Autores principales: Droho, Steven, Cuda, Carla M., Perlman, Harris, Lavine, Jeremy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433398/
https://www.ncbi.nlm.nih.gov/pubmed/34508129
http://dx.doi.org/10.1038/s41598-021-97522-x