Cargando…
Macrophage-derived interleukin-6 is necessary and sufficient for choroidal angiogenesis
Neovascular age-related macular degeneration (nAMD) commonly causes vision loss from aberrant angiogenesis, termed choroidal neovascularization (CNV). Interleukin-6 (IL6) is a pro-inflammatory and pro-angiogenic cytokine that is correlated with AMD progression and nAMD activity. We hypothesize that...
Autores principales: | Droho, Steven, Cuda, Carla M., Perlman, Harris, Lavine, Jeremy A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433398/ https://www.ncbi.nlm.nih.gov/pubmed/34508129 http://dx.doi.org/10.1038/s41598-021-97522-x |
Ejemplares similares
-
Monocyte-Derived Macrophages Are Necessary for Beta-Adrenergic Receptor-Driven Choroidal Neovascularization Inhibition
por: Droho, Steven, et al.
Publicado: (2019) -
CD11c(+) macrophages are proangiogenic and necessary for experimental choroidal neovascularization
por: Droho, Steven, et al.
Publicado: (2023) -
Ocular macrophage origin and heterogeneity during steady state and experimental choroidal neovascularization
por: Droho, Steven, et al.
Publicado: (2020) -
Dendritic cells play no significant role in the laser-induced choroidal neovascularization model
por: Droho, Steven, et al.
Publicado: (2021) -
NR4A1 deletion promotes pro-angiogenic polarization of macrophages derived from classical monocytes in a mouse model of neovascular age-related macular degeneration
por: Droho, Steven, et al.
Publicado: (2023)