Cargando…

Recognition of high-specificity hERG K+ channel inhibitor-induced arrhythmia in cardiomyocytes by automated template matching

Cardiovascular disease (CVD) is the number one cause of death in humans. Arrhythmia induced by gene mutations, heart disease, or hERG K(+) channel inhibitors is a serious CVD that can lead to sudden death or heart failure. Conventional cardiomyocyte-based biosensors can record extracellular potentia...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Hao, Li, Hongbo, Wei, Xinwei, Zhang, Tao, Xiang, Yuting, Fang, Jiaru, Wu, Peiran, Xie, Xi, Wang, Ping, Hu, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433465/
https://www.ncbi.nlm.nih.gov/pubmed/34567738
http://dx.doi.org/10.1038/s41378-021-00251-4