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Recognition of high-specificity hERG K+ channel inhibitor-induced arrhythmia in cardiomyocytes by automated template matching
Cardiovascular disease (CVD) is the number one cause of death in humans. Arrhythmia induced by gene mutations, heart disease, or hERG K(+) channel inhibitors is a serious CVD that can lead to sudden death or heart failure. Conventional cardiomyocyte-based biosensors can record extracellular potentia...
Autores principales: | Wang, Hao, Li, Hongbo, Wei, Xinwei, Zhang, Tao, Xiang, Yuting, Fang, Jiaru, Wu, Peiran, Xie, Xi, Wang, Ping, Hu, Ning |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433465/ https://www.ncbi.nlm.nih.gov/pubmed/34567738 http://dx.doi.org/10.1038/s41378-021-00251-4 |
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