DNA-encoded chemistry technology yields expedient access to SARS-CoV-2 M(pro) inhibitors

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has killed more than 4 million humans globally, but there is no bona fide Food and Drug Administration–approved drug-like molecule to impede the COVID-19 pandemic. The sluggish pace of traditional therapeutic discovery is poorly suited to...

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Detalles Bibliográficos
Autores principales: Chamakuri, Srinivas, Lu, Shuo, Ucisik, Melek Nihan, Bohren, Kurt M., Chen, Ying-Chu, Du, Huang-Chi, Faver, John C., Jimmidi, Ravikumar, Li, Feng, Li, Jian-Yuan, Nyshadham, Pranavanand, Palmer, Stephen S., Pollet, Jeroen, Qin, Xuan, Ronca, Shannon E., Sankaran, Banumathi, Sharma, Kiran L., Tan, Zhi, Versteeg, Leroy, Yu, Zhifeng, Matzuk, Martin M., Palzkill, Timothy, Young, Damian W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Physical Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433497/
https://www.ncbi.nlm.nih.gov/pubmed/34426525
http://dx.doi.org/10.1073/pnas.2111172118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433497/
https://www.ncbi.nlm.nih.gov/pubmed/34426525
http://dx.doi.org/10.1073/pnas.2111172118

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