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Bcl6 controls meningeal Th17–B cell interaction in murine neuroinflammation

Ectopic lymphoid tissue containing B cells forms in the meninges at late stages of human multiple sclerosis (MS) and when neuroinflammation is induced by interleukin (IL)-17 producing T helper (Th17) cells in rodents. B cell differentiation and the subsequent release of class-switched immunoglobulin...

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Detalles Bibliográficos
Autores principales: Hartlehnert, Maike, Börsch, Anna-Lena, Li, Xiaolin, Burmeister, Miriam, Gerwien, Hanna, Schafflick, David, Heming, Michael, Lu, I-Na, Narayanan, Venu, Strecker, Jan-Kolja, Kolz, Anna, Peters, Anneli, Wu, Gregory F., Wiendl, Heinz, Sorokin, Lydia, Meyer zu Horste, Gerd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433502/
https://www.ncbi.nlm.nih.gov/pubmed/34479995
http://dx.doi.org/10.1073/pnas.2023174118