Amyloid particles facilitate surface-catalyzed cross-seeding by acting as promiscuous nanoparticles

Amyloid seeds are nanometer-sized protein particles that accelerate amyloid assembly as well as propagate and transmit the amyloid protein conformation associated with a wide range of protein misfolding diseases. However, seeded amyloid growth through templated elongation at fibril ends cannot expla...

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Detalles Bibliográficos
Autores principales: Koloteva-Levine, Nadejda, Aubrey, Liam D., Marchante, Ricardo, Purton, Tracey J., Hiscock, Jennifer R., Tuite, Mick F., Xue, Wei-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433567/
https://www.ncbi.nlm.nih.gov/pubmed/34462352
http://dx.doi.org/10.1073/pnas.2104148118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433567/
https://www.ncbi.nlm.nih.gov/pubmed/34462352
http://dx.doi.org/10.1073/pnas.2104148118

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