The Antagonist pGlu-βGlu-Pro-NH(2) Binds to an Allosteric Site of the Thyrotropin-Releasing Hormone Receptor

After we identified pGlu-βGlu-Pro-NH(2) as the first functional antagonist of the cholinergic central actions of the thyrotropin-releasing hormone (TRH, pGlu-His-Pro-NH(2)), we became interested in finding the receptor-associated mechanism responsible for this antagonism. By utilizing a human TRH re...

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Detalles Bibliográficos
Autores principales: De La Cruz, Daniel L., Prokai, Laszlo, Prokai-Tatrai, Katalin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433856/
https://www.ncbi.nlm.nih.gov/pubmed/34500828
http://dx.doi.org/10.3390/molecules26175397

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8433856/
https://www.ncbi.nlm.nih.gov/pubmed/34500828
http://dx.doi.org/10.3390/molecules26175397

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